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Updated: Aug 7, 2025

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Primary MRSA Myositis Mimicking Septic Arthritis
Mohammad Abu-Abaa1, Amy Pulikeyil1, Hassaan Arshad1
1Capital Health Regional Medical Center, Internal Medicine Residency Program, USA.
Abstract:
As the incidence of bacterial myositis and pyomyositis in the United States is rising, we aim to highlight the presentation of bacterial myositis which is known as a great imitator in tropical regions. This is a case report of a 61-year-old female patient with poorly controlled diabetes who presented initially with lateral hip pain and tenderness. This was initially believed to be septic arthritis and warranted arthrocentesis. What makes this case interesting is that what was believed to be a primary community-acquired MRSA myositis, which progressed to a life-threatening septic shock, happened in a nontropical area (Northeastern USA) and in a patient with no underlying recent muscle injury. This case serves to remind clinicians that infectious myositis is gaining more incidence in nontropical regions and can masquerade as septic arthritis, requiring a high index of suspicion. Normal muscle enzymes like CK and aldolase do not rule out myositis.
Insights
Bacterial myositis, often mimicking septic arthritis, is increasingly seen outside tropical areas. Early suspicion is crucial, as normal muscle enzymes do not exclude this serious infection.
Area of Science:
- Infectious Diseases
- Rheumatology
- Musculoskeletal Infections
Background:
- Bacterial myositis and pyomyositis incidence is rising in the United States.
- Bacterial myositis is known as a 'great imitator,' particularly in tropical regions.
- This condition can present atypically, even in non-tropical areas without apparent muscle injury.
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