Behaviourally dependent modulation of lateral geniculate unit activity in the freely moving cat

In 120 neurons of the cat's dorsal lateral geniculate body (dLGB), spontaneous and light-evoked activity was analysed in order to obtain further information on firing characteristics during different behavioural states (quietly sitting, locomotion). Experiments were carried out in freely moving cats, using wireless methods for simultaneous registration of single unit activity and locomotion. During locomotion, an enhancement of neuronal single and pool activity was observed. During locomotor activity, flash-evoked responses were modulated, an increase of response amplitude and a decrease of peak latency in the peristimulus time histogram occurred. The results demonstrate a facilitatory influence on spontaneous and light-evoked activity of dLGB neurones during locomotion. They suggest a non-visual phasic modulation of retino-geniculo-cortical information transfer.