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Updated: Aug 7, 2025

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Case report of a very rare primary malignant bone tumor: Mixed type maxillary osteosarcoma
Eko Ardianto Margiono1, Sri Andreani1
1Divison of Neuro Radiology and Head & Neck Radiology, Department of Radiology, Faculty of Medicine, Universitas Airlangga-Dr Soetomo Academic General Hospital, Jalan Mayjen. Prof Dr Moestopo 47, Surabaya 60131, Indonesia.
Abstract:
Osteosarcoma (OS) is the most common primary malignant bone tumor, accounting for approximately 20% of all primary bone malignancies. OS affects 2-4.8 in 1,000,000 individuals annually and is more common in men than women (1.5:1 ratio). The most common locations include the femur (42%), the tibia (19%), and the humerus (10%), whereas other potential sites include the skull or jaw (8%) and the pelvis (8%). We report a very rare case in a 48-year-old female who presented with swelling of the left cheek accompanied by palpable solid mass, with the final diagnosis of mixed type maxillary OS was confirmed from a surgical biopsy.

