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Quincke's disease: an unusual pathology
Gabriel Atan Sanchez1, Madison Boot1, Abdul Lathif1
1Wagga Wagga Base Hospital, Wagga Wagga, Ears Nose and Throat Department, NSW, Australia.
Journal of Surgical Case Reports
|March 10, 2023
Summary
Recurrent Quincke's disease, a rare condition causing uvula swelling, can be aggravated by cold weather. Surgical intervention with partial uvulectomy may be considered when other treatments fail.
Area of Science:
- Otolaryngology
- Allergy and Immunology
Background:
- Quincke's disease, a form of angioedema, can affect the oropharynx.
- Recurrent episodes necessitate investigation into underlying causes and effective management strategies.
Observation:
- A 50-year-old male presented with recurrent, severe uvula swelling and sore throat, exacerbated by cold weather.
- This was his third episode of Quincke's disease, with no compromise to his airway.
Findings:
- Intravenous hydrocortisone and dexamethasone, along with paracetamol, provided symptomatic relief within 12 hours.
- Despite thorough investigation, a specific cause for the recurrent Quincke's disease could not be identified.
Implications:
- Partial uvulectomy was planned as a potential treatment option for refractory Quincke's disease.
- This case highlights the diagnostic challenges and varied treatment approaches for recurrent angioedema affecting the uvula.
