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Related Experiment Video

Updated: Aug 7, 2025

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
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Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

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Automatic Segmentation of Periapical Radiograph Using Color Histogram and Machine Learning for Osteoporosis

Rini Widyaningrum1, Enny Itje Sela2, Reza Pulungan3

  • 1Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.

International Journal of Dentistry
|March 10, 2023
PubMed
Summary

This study introduces an automated method using dental X-rays and machine learning to detect osteoporosis. The best approach combined K-means segmentation with a multilayer perceptron classifier, achieving high accuracy in identifying bone density loss.

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Bone Health

Background:

  • Osteoporosis causes bone loss, reduced bone mineral density (BMD), and increased fracture risk.
  • Dental periapical radiographs can reveal changes in trabecular bone structure associated with osteoporosis.

Purpose of the Study:

  • To develop and evaluate an automatic trabecular bone segmentation method for osteoporosis detection using periapical radiographs.
  • To compare K-means and Fuzzy C-means segmentation algorithms combined with machine learning classifiers.

Main Methods:

  • The study utilized 120 regions of interest (ROI) from periapical radiographs, split into training and testing datasets.
  • An automated method involving grayscale conversion, color histogram segmentation, and pixel distribution extraction was employed.
  • K-means and Fuzzy C-means were compared for segmentation, with results fed into decision tree, naive Bayes, and multilayer perceptron classifiers.

Main Results:

  • The combination of K-means segmentation and a multilayer perceptron classifier demonstrated the highest diagnostic performance.
  • This optimal method achieved an accuracy of 90.48%, specificity of 90.90%, and sensitivity of 90.00% on the testing dataset.

Conclusions:

  • The proposed automated method using K-means segmentation and multilayer perceptron shows significant potential for osteoporosis detection.
  • This technique offers a valuable contribution to medical and dental image analysis for early osteoporosis diagnosis.