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Related Concept Videos

Tissues01:25

Tissues

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Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
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Plant Tissues01:18

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Plants are multicellular eukaryotes with tissue systems made of various cell types that carry out specific functions. Different tissues work together to perform a unique function and form an organ. Organs working together form organ systems. Vascular plants have two distinct organ systems: a shoot system and a root system. The shoot system consists of two portions: the vegetative (non-reproductive) parts of the plant, such as the leaves and the stems, and the reproductive parts of the plant,...
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Classification of Epithelial Tissues: Overview01:22

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Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
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Plant Cells and Tissues02:01

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Plant tissues are collections of similar cells performing related functions. Different plant tissues will have their own specialized roles and can be combined with other tissues to form organs such as flowers, fruit, stem, and leaves. Two major types of plant tissue include meristematic and permanent tissue.
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Classification of Epithelial Tissues: Glandular Epithelium01:20

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The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
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Histology of the Gastrointestinal (GI) Tract01:20

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The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
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Working with Human Tissues for Translational Cancer Research
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General histological woes: Encore. Tissues, please.

Paul E Neumann1,2, Eve E Neumann3

  • 1Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA.

Clinical Anatomy (New York, N.Y.)
|March 10, 2023
PubMed
Summary
This summary is machine-generated.

This study revisits the four basic tissue dogma in histology, proposing a revised human tissue classification for improved accuracy. It addresses criticisms, highlighting the need for a more precise tissue taxonomy beyond basic cell arrays.

Keywords:
anatomical ontologyanatomyhistologysystematic anatomytissue

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Area of Science:

  • Histology
  • Cell Biology
  • Taxonomy

Background:

  • The traditional four basic tissue types (epithelial, connective, muscle, nervous) have limitations.
  • Certain human tissues are not adequately classified within this dogma.
  • A provisional reclassification was previously proposed to enhance tissue taxonomy.

Purpose of the Study:

  • To address criticisms of a revised human tissue classification.
  • To evaluate the utility of the four basic tissue dogma versus a revised classification.
  • To clarify misconceptions about tissue definition in medical education and clinical practice.

Main Methods:

  • Comparative analysis of existing and revised tissue classifications.
  • Review of criticisms regarding the proposed reclassification.
  • Examination of the definition of 'tissue' in histological contexts.

Main Results:

  • Criticisms of the revised classification were analyzed.
  • The study highlights a common misconception of tissues as merely cell arrays.
  • The limitations of the traditional four-tissue dogma persist.

Conclusions:

  • The proposed reclassification aims for greater precision in human tissue taxonomy.
  • Rethinking the definition of tissue is crucial for accurate classification.
  • The traditional dogma may be less useful than a more comprehensive system.