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Characteristics of Fatal Poisonings Among Infants and Young Children in the United States
Christopher E Gaw1,2,3, Allison E Curry1,2, Kevin C Osterhoudt1,2,3
1Divisions of Emergency Medicine.
Insights
Fatal child poisonings are preventable. Opioids are the leading cause, with over-the-counter medications also contributing significantly to these tragic deaths in young children.
Area of Science:
- Pediatric Toxicology
- Public Health
- Child Safety
Background:
- Fatal poisoning is a significant, yet preventable, cause of death in young children.
- Understanding the circumstances surrounding these deaths is crucial for developing effective prevention strategies.
Purpose of the Study:
- To characterize fatal pediatric poisonings using data from child death reviews.
- To identify demographic, supervisory, and substance-related factors associated with these fatalities.
Main Methods:
- Analysis of data from the National Fatality Review-Case Reporting System (NFR-CRS) for children aged 5 years and younger.
- Inclusion of data from 40 states spanning the years 2005 to 2018.
- Descriptive statistical analysis of demographic, death investigation, and substance-related variables.
Main Results:
- 731 poisoning-related fatalities were reported among children aged 5 years and younger between 2005 and 2018.
- Opioids were the most frequent substances involved (47.3%), followed by over-the-counter medications (14.8%).
- Fatalities predominantly occurred in the home (65.1%), with a notable proportion involving infants under 1 year old (42.1%).
Conclusions:
- Opioids represent the primary substance involved in fatal pediatric poisonings.
- Over-the-counter medications remain a significant factor in child fatalities, underscoring the need for ongoing vigilance.
- Tailored prevention measures are essential to reduce the incidence of fatal poisonings in young children.
Background And Objectives:
Fatal poisoning is a preventable cause of death among young children. Understanding factors surrounding these deaths will inform future prevention efforts. Our objective was to describe the characteristics of fatal pediatric poisonings using child death review data.
Methods:
We acquired data from 40 states participating in the National Fatality Review-Case Reporting System on deaths attributed to poisonings among children aged ≤5 years from 2005 to 2018. We analyzed select demographic, supervisor, death investigation, and substance-related variables using descriptive statistics.
Results:
During the study period, 731 poisoning-related fatalities were reported by child death reviews to the National Fatality Review-Case Reporting System. Over two-fifths (42.1%, 308 of 731) occurred among infants aged <1 year, and most fatalities (65.1%, 444 of 682) occurred in the child's home. One-sixth of children (97 of 581) had an open child protective services case at time of death. Nearly one-third (32.2%, 203 of 631) of children were supervised by an individual other than the biological parent. Opioids (47.3%, 346 of 731) were the most common substance contributing to death, followed by over-the-counter pain, cold, and allergy medications (14.8%, 108 of 731). Opioids accounted for 24.1% (7 of 29) of the substances contributing to deaths in 2005 compared with 52.2% (24 of 46) in 2018.
Conclusions:
Opioids were the most common substances contributing to fatal poisonings among young children. Over-the-counter medications continue to account for pediatric fatalities even after regulatory changes. These data highlight the importance of tailored prevention measures to further reduce fatal child poisonings.
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