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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Machine Learning

Background:

  • Lack of transparency in artificial intelligence (AI) models hinders medical applications.
  • Explainable AI (XAI) is crucial for understanding and validating AI-driven medical diagnoses.
  • Accurate and rapid diagnosis of brain tumors is vital for patient outcomes.

Purpose of the Study:

  • To develop and evaluate an XAI-based model for faster and more accurate brain tumor diagnosis.
  • To enhance the safety and reliability of AI in medical diagnostics.
  • To improve upon existing state-of-the-art methods for brain tumor detection.

Main Methods:

  • Utilized DenseNet201 as a pre-trained feature extractor for brain MR images.
  • Employed GradCAM for tumor segmentation and an exemplar method for feature extraction.
  • Implemented an iterative neighborhood component (INCA) feature selector and Support Vector Machine (SVM) with 10-fold cross-validation for classification.

Main Results:

  • Achieved high diagnostic accuracy: 98.65% on Dataset I (Kaggle) and 99.97% on Dataset II (Figshare).
  • The proposed XAI model demonstrated superior performance compared to current state-of-the-art methods.
  • Successfully segmented tumor areas and extracted relevant features for classification.

Conclusions:

  • The developed XAI model offers a transparent and accurate approach to brain tumor diagnosis.
  • This method can serve as a valuable tool to assist radiologists in clinical practice.
  • XAI integration significantly improves the trustworthiness and efficacy of AI in neuro-oncology.