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Induction of Apoptosis and Decrease of Autophagy in Colon Cancer Cells by an Extract of Lyophilized Mango Pulp

Gustavo Argenor Lozano-Casabianca1, Sandra Sulay Arango-Varela2, María Elena Maldonado-Celis1

  • 1School of Nutrition and Dietetics, University of Antioquia, Medellín 050010, Colombia.

International Journal of Environmental Research and Public Health
|March 11, 2023
PubMed

Keywords:
Mangifera indica L.apoptosisautophagycolorectal cancermatrix metalloproteinases

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Apoptosis is a combination of two Greek words, 'apo' and 'ptosis,' meaning separation and falling off, respectively. Hippocrates used this word to describe gangrene, which was caused due to bandaging of fractured bones. Apoptosis was distinguished from necrosis in 1970 when John Kerr reported observations of morphological changes occurring during apoptosis. During one experiment, he observed that the disruption of blood supply to the liver tissue resulted in a size...
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