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Association between Toxoplasma gondii Infection and Type-1 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Ashley Catchpole1, Brinley N Zabriskie2, Pierce Bassett1
1The Neuroscience Center, Brigham Young University, Provo, UT 84602, USA.
Toxoplasma gondii infection may be linked to type-1 diabetes. This systematic review found a potential positive association, but further research is needed to confirm the relationship and its directionality.
Area of Science:
- Immunology
- Infectious Diseases
- Endocrinology
Background:
- Type-1 diabetes involves pancreatic beta cell destruction and is linked to various complications.
- The protozoal parasite *Toxoplasma gondii* has been previously associated with type-1 diabetes.
- Understanding this potential link is crucial for public health and disease management.
Conclusions:
- *Toxoplasma gondii* infection may be positively associated with type-1 diabetes.
- Further research is necessary to elucidate the causal relationship and underlying mechanisms.
- Future studies should investigate whether diabetes influences *Toxoplasma gondii* susceptibility or vice versa, or if both occur.
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