Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

382
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
382

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lived Experiences of Patients With Rare Diseases and Healthcare System Barriers: A Phenomenological Study.

Journal of nursing management·2026
Same author

The release of catecholamines to the cytosol and the exocytosis of secretory vesicles triggered by IP<sub>3</sub> in chromaffin cells.

American journal of physiology. Cell physiology·2025
Same author

Increasing Temperature Activates TREK Potassium Currents in Vagal Afferent Neurons from the Nodose Ganglion.

International journal of molecular sciences·2025
Same author

Experiences of Females With Late Diagnosis of Autism: Descriptive Qualitative Study.

Nursing research·2025
Same author

Effectiveness of a Haemorrhage-Control Task Simulator for Training Nursing Students: A Quasi-Experimental before-after Study.

Journal of nursing management·2025
Same author

Applications of Artificial Intelligence in Nursing Care: A Systematic Review.

Journal of nursing management·2025
Same journal

Correction: Grewal et al. Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications. <i>Int. J. Environ. Res. Public Health</i> 2026, <i>23</i>, 241.

International journal of environmental research and public health·2026
Same journal

Drinking Water Quality and Health Risk Assessment in Rural Ghana: Evidence from North-East and North Gonja Districts in the Savannah Region.

International journal of environmental research and public health·2026
Same journal

Physical Activity of University Students During COVID-19 Restrictions: Evidence from Poland.

International journal of environmental research and public health·2026
Same journal

Assessment of Occupational Health and Safety Hazards in Mosquito Control Personnel in North Carolina and Virginia, USA.

International journal of environmental research and public health·2026
Same journal

Association Between Dysfunctional Parenting Practices and Suspected Gaming Disorder Among Japanese Male Junior High School Students: A Cross-Sectional Study of Parental Assessment.

International journal of environmental research and public health·2026
Same journal

A National Virtual Peer Support Group for Women Veterans Living with Breast Cancer: Lessons from the Field.

International journal of environmental research and public health·2026
See all related articles

Related Experiment Video

Updated: Aug 7, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.7K

Changes in Gut Microbiota and Multiple Sclerosis: A Systematic Review.

Alba Ordoñez-Rodriguez1, Pablo Roman2,3, Lola Rueda-Ruzafa2

  • 1The Virgen de la Arrixaca Hospital, 30120 Murcia, Spain.

International Journal of Environmental Research and Public Health
|March 11, 2023
PubMed
Summary
This summary is machine-generated.

Multiple sclerosis (MS) is linked to gut microbiota changes, with reduced beneficial bacteria and short-chain fatty acids observed. These alterations may drive chronic inflammation in MS, suggesting microbiome manipulation for future therapies.

Keywords:
gut microbiotamicrobiome: short-chain fatty acidmultiple sclerosis

More Related Videos

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.9K
Analysis of Fecal Microbiota Dynamics in Lupus-Prone Mice Using a Simple, Cost-Effective DNA Isolation Method
05:28

Analysis of Fecal Microbiota Dynamics in Lupus-Prone Mice Using a Simple, Cost-Effective DNA Isolation Method

Published on: May 2, 2022

2.2K

Related Experiment Videos

Last Updated: Aug 7, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.7K
Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.9K
Analysis of Fecal Microbiota Dynamics in Lupus-Prone Mice Using a Simple, Cost-Effective DNA Isolation Method
05:28

Analysis of Fecal Microbiota Dynamics in Lupus-Prone Mice Using a Simple, Cost-Effective DNA Isolation Method

Published on: May 2, 2022

2.2K

Area of Science:

  • Neuroimmunology
  • Microbiome Research
  • Gastroenterology

Background:

  • Multiple sclerosis (MS) is a chronic, inflammatory, neurodegenerative autoimmune disease affecting the central nervous system.
  • MS is a leading cause of non-traumatic neurological disability in young adults, particularly women.
  • Emerging evidence suggests a potential link between MS pathogenesis and the gut microbiota, though clinical data are limited.

Approach:

  • A systematic review was conducted in Q1 2022 to investigate the relationship between gut microbiota and MS.
  • Literature search performed across PubMed, Scopus, ScienceDirect, Proquest, Cochrane, and CINAHL using keywords: "multiple sclerosis", "gut microbiota", and "microbiome".
  • 12 relevant articles were selected and analyzed for findings on microbial diversity, taxonomy, and short-chain fatty acid (SCFA) profiles in MS patients.

Key Points:

  • The review identified significant alterations in gut microbiota composition in MS patients compared to healthy controls.
  • Specific bacterial taxa showed decreased abundance (e.g., Firmicutes, Bifidobacterium) and increased abundance (e.g., Bacteroidetes, Akkermansia).
  • A general reduction in SCFA-producing bacteria and SCFAs, particularly butyrate, was noted, potentially contributing to MS-related inflammation.

Conclusions:

  • Gut dysbiosis is a consistent finding in multiple sclerosis patients.
  • Alterations in SCFA-producing bacteria may play a role in the chronic inflammation characteristic of MS.
  • Future research should focus on characterizing and manipulating the MS-associated microbiome for potential diagnostic and therapeutic applications.