Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Holter Monitor: 24-Hour Monitoring01:23

Holter Monitor: 24-Hour Monitoring

94
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
94
Pulse rhythm01:30

Pulse rhythm

872
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
872

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optoelectronic microwave oscillator based on integrated Si-ITO plasmonic modulator.

Scientific reports·2026
Same author

Irf5 Knockdown in Bone Marrow-Derived Macrophages Favors M1-to-M2 Transition.

Cells·2026
Same author

Anti-Cancer Outcome of Glucocorticoid Receptor Transrepression by Synephrine Derivatives in Hematological Malignancies.

International journal of molecular sciences·2025
Same author

Delivery of Lipid Nanoparticles with ROS Probes for Improved Visualization of Hepatocellular Carcinoma.

Biomedicines·2023
Same author

4-Methylumbelliferone Targets Revealed by Public Data Analysis and Liver Transcriptome Sequencing.

International journal of molecular sciences·2023
Same author

Macrophage <i>In Vitro</i> and <i>In Vivo</i> Tracking via Anchored Microcapsules.

ACS applied materials & interfaces·2022

Related Experiment Video

Updated: Aug 7, 2025

Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature
05:33

Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature

Published on: June 19, 2019

8.6K

Cortisol Monitoring Devices toward Implementation for Clinically Relevant Biosensing In Vivo.

Pavel A Kusov1, Yuri V Kotelevtsev2, Vladimir P Drachev1

  • 1Center for Engineering Physics, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.

Molecules (Basel, Switzerland)
|March 11, 2023
PubMed
Summary

Continuous cortisol monitoring is needed for personalized treatment of the hypothalamic-pituitary-adrenal (HPA) axis. Current methods are limited, but new sensor platforms show promise for real-time HPA-axis regulation.

Keywords:
cortisol continuous monitoringin vivo biosensornanomaterialsneuroendocrinology

More Related Videos

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

9.7K
Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds
10:07

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds

Published on: November 6, 2015

13.5K

Related Experiment Videos

Last Updated: Aug 7, 2025

Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature
05:33

Measuring Biophysical and Psychological Stress Levels Following Visitation to Three Locations with Differing Levels of Nature

Published on: June 19, 2019

8.6K
Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

9.7K
Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds
10:07

Thermal Imaging to Study Stress Non-invasively in Unrestrained Birds

Published on: November 6, 2015

13.5K

Area of Science:

  • Endocrinology
  • Neuroendocrinology
  • Biomedical Engineering

Background:

  • Cortisol, a key steroid hormone, regulates metabolism, stress, and immunity.
  • Its production in the adrenal cortex is controlled by the hypothalamic-pituitary-adrenal (HPA) axis via a circadian rhythm and negative feedback loop.
  • Disruptions in HPA-axis function are linked to psychiatric, cardiovascular, metabolic, and inflammatory disorders, impacting quality of life.

Purpose of the Study:

  • To review and compare existing platforms for direct cortisol measurement in biological fluids.
  • To discuss strategies for developing continuous, real-time cortisol monitoring.
  • To highlight the necessity of such a device for personalized HPA-axis pharmacotherapy.

Main Methods:

  • Review of recent advances in cortisol sensing technologies.
  • Comparison of different platforms for direct cortisol detection in biological samples.
  • Discussion of approaches enabling continuous cortisol measurement.

Main Results:

  • Current laboratory cortisol measurements, primarily ELISA, are well-established but not continuous.
  • Several promising sensor platforms are emerging for direct cortisol detection.
  • The development of continuous cortisol monitoring is a significant unmet need.

Conclusions:

  • A continuous cortisol monitoring device is essential for personalized pharmacological correction of HPA-axis dysfunction.
  • Real-time cortisol level tracking will enable precise 24-hour management of HPA-axis activity.
  • Advances in sensor technology are paving the way for this critical clinical tool.