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Cyclothymic disorder and bromocriptine: predisposing factors for postpartum mania?
1Department of Psychiatry, Uniformed Services University of the Health Sciences, F. Edward Hebert School of Medicine, Bethesda, MD 20814-4799.
Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
|November 1, 1987
Summary
Postpartum women, especially those with affective disorders, are at risk for manic episodes. Bromocriptine, used for lactation prevention, may trigger these reactions in susceptible individuals.
Area of Science:
- Psychiatry
- Neuroscience
- Women's Health
Background:
- Postpartum period presents significant psychological and physiological stress for women.
- Women with a history of affective disorders, including cyclothymia and dysthymia, are more vulnerable to postpartum mood disturbances.
- Certain medications, like bromocriptine and sympathomimetic drugs, are used during the puerperium and may precipitate manic episodes.
Observation:
- This case report details a postpartum manic episode.
- The patient had a history of cyclothymia.
- Bromocriptine, a dopamine agonist, was prescribed to the patient for lactation prevention.
Findings:
- The patient experienced a manic episode during the postpartum period.
- Bromocriptine administration was identified as a potential catalyst for the manic episode in this cyclothymic woman.
- The use of bromocriptine in the puerperal period warrants careful consideration in women with a history of affective disorders.
Implications:
- Increased vigilance is necessary for postpartum women with a history of affective disorders.
- Healthcare providers should carefully assess the risks and benefits of medications like bromocriptine in this population.
- Early identification and intervention are crucial for managing postpartum mood episodes and preventing recurrence.