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[Evaluation of the features of left ventricular contractility in elderly patients with high-risk hypertension.]

O A Osipova1, E V Gosteva1, A N Khachaturov1

  • 1Belgorod State National Research University, 85 Pobedy str., Belgorod 308015, Russian Federation, е-mail: osipova@bsu.edu.ru.

Advances in Gerontology = Uspekhi Gerontologii
|March 11, 2023
PubMed

Insights

Elderly patients with hypertension experiencing ischemic stroke (AI) show more severe left ventricular (LV) diastolic dysfunction, specifically pseudonormal type, compared to middle-aged individuals.

Area of Science:

  • Cardiology
  • Geriatrics
  • Neurology

Context:

  • Arterial hypertension (AH) is a significant risk factor for ischemic stroke (AI).
  • Left ventricular (LV) diastolic function is crucial for cardiac health and can be impaired by hypertension.
  • Age-related changes may influence the impact of hypertension on cardiac function post-stroke.

Purpose:

  • To investigate the specific characteristics of left ventricular diastolic function in elderly patients with hypertension following an ischemic stroke.
  • To compare these features with those in middle-aged patients with hypertension and a history of ischemic stroke.

Summary:

  • The study examined 68 elderly and 65 middle-aged hypertensive patients post-AI using daily blood pressure monitoring and echocardiography.
  • Elderly patients exhibited a higher prevalence of type 2 (pseudonormal) diastolic dysfunction (45.8% more often, p<0.001).
  • Key differences included longer isovolumic relaxation time, altered myocardial velocity during atrial contraction, and a lower E/A ratio in the elderly group.

Impact:

  • The findings highlight significantly pronounced LV diastolic dysfunction in elderly hypertensive patients after ischemic stroke.
  • This underscores the need for targeted cardiac assessments and management strategies in this vulnerable population.
  • Understanding these age-related differences can inform clinical practice and improve patient outcomes.

Keywords:
arterial hypertensioncontractility of the left ventricleischemic strokeold age

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