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Related Experiment Video

Updated: Aug 7, 2025

Estimating Vestibular Perceptual Thresholds Using a Six-Degree-Of-Freedom Motion Platform
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Pharmacological interventions for persistent postural-perceptual dizziness (PPPD).

Katie E Webster1, Natasha A Harrington-Benton2, Owen Judd3

  • 1Cochrane ENT, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.

The Cochrane Database of Systematic Reviews
|March 12, 2023
PubMed
Summary
This summary is machine-generated.

No studies met the criteria for this review on pharmacological treatments for persistent postural-perceptual dizziness (PPPD). Further research is needed to determine the effectiveness and safety of these interventions for this chronic balance disorder.

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Area of Science:

  • Neurology
  • Otolaryngology
  • Pharmacology

Background:

  • Persistent postural-perceptual dizziness (PPPD) is a recently defined chronic balance disorder impacting quality of life.
  • Symptoms include subjective unsteadiness and dizziness exacerbated by standing and visual stimuli.
  • Optimal treatment strategies for PPPD remain largely unknown.

Conclusions:

  • Currently, no evidence supports the use of SSRIs or SNRIs for treating PPPD based on placebo-controlled RCTs.
  • Further research is essential to establish effective and safe pharmacological treatments for PPPD.
  • The effectiveness and adverse effects of potential PPPD medications require rigorous investigation.