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ACR-ARS Practice Parameter for the Performance of Total Body Irradiation
Michael Reilly1, Savita V Dandapani2, Kiran A Kumar3
1University of California, Irvine, Irvine, CA.
American Journal of Clinical Oncology
|March 13, 2023
Summary
This practice parameter offers updated guidance on conventional and modulated total body irradiation (TBI). It emphasizes dose rate, imaging, and lung dose evaluation for improved TBI program design and patient outcomes.
Area of Science:
- Radiation Oncology
- Medical Physics
Background:
- Provides an updated reference literature for total body irradiation (TBI).
- Covers both conventional and evolving volumetric modulated TBI techniques.
Framework:
- Developed collaboratively by the American College of Radiology (ACR) and the American Radium Society (ARS).
- Follows the established ACR process for developing practice parameters and technical standards.
Implementation:
- Addresses dose rate dependence in conventional and rotational TBI techniques.
- Includes the role of imaging in patient setup and inhomogeneity corrections.
- Highlights the importance of evaluating mean lung dose to mitigate toxicity.
Implications:
- Serves as a tool for designing and evaluating TBI programs.
- Facilitates close interaction and coordination among multidisciplinary healthcare teams.
- Aims to improve the effectiveness and safety of total body irradiation treatments.

