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Patterns of Metastatic Recurrence of Genetically Confirmed Myxoid Liposarcoma
Pauliina Homsy1, Tom Böhling2, Anne Seitsonen3
1Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. pauliina.homsy@hus.fi.
Annals of Surgical Oncology
|March 13, 2023
Summary
Myxoid liposarcomas (MLSs) frequently metastasize to soft tissues and the abdomen, not just the lungs. This suggests whole-body imaging is crucial for staging and follow-up of MLS patients.
Area of Science:
- Oncology
- Medical Imaging
- Genetics
Background:
- Most sarcomas spread to the lungs, with chest imaging as standard staging.
- Myxoid liposarcomas (MLSs) are rare and tend to metastasize to unusual sites.
- Current staging may miss extrapulmonary metastases in MLS.
Conclusions:
- Myxoid liposarcomas (MLSs) commonly metastasize to soft tissues and the abdomen.
- Standard lung-focused imaging may be insufficient for MLS.
- Whole-body imaging is recommended for initial assessment and follow-up of MLS patients.
