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Related Concept Videos

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Updated: Aug 7, 2025

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Malignancy in pregnancy: Multimodality imaging and treatment.

Trinh Nguyen1, Priya R Bhosale1, Lorena Cassia2

  • 1Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Cancer
|March 13, 2023
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Diagnosing cancer in pregnant patients presents unique challenges. This review covers imaging, diagnosis, and treatment strategies for maternal cancer, balancing fetal safety with diagnostic needs.

Keywords:
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Area of Science:

  • Oncology
  • Radiology
  • Maternal-Fetal Medicine

Background:

  • Cancer diagnosis in pregnancy is rising due to increased maternal age and advanced screening.
  • Incidental cancer detection during prenatal screening is becoming more common.
  • Managing cancer in pregnant patients requires specialized, interdisciplinary approaches.

Purpose of the Study:

  • To review multimodality imaging and safety in pregnant cancer patients.
  • To discuss current guidelines for ionizing radiation imaging.
  • To present common and uncommon cancers in pregnancy with diagnostic imaging strategies.

Main Methods:

  • Literature review of diagnostic imaging techniques and safety considerations.
  • Analysis of current guidelines for ionizing radiation use in pregnancy.
  • Case series presentation of cancers in pregnancy with imaging recommendations.

Main Results:

  • Multimodality imaging is crucial for diagnosis, staging, and treatment planning.
  • Balancing fetal radiation exposure with diagnostic image quality is a key challenge.
  • Evolving guidelines and novel therapies require continuous adaptation.

Conclusions:

  • Management of cancer in pregnancy is complex and requires a multidisciplinary team.
  • Adherence to evolving imaging guidelines and safety protocols is essential.
  • Novel anticancer therapies necessitate careful consideration of maternal and fetal outcomes.