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Steroid receptors and human endometrial carcinoma: studies in a nude mouse model

P G Satyaswaroop1, R J Zaino, R Mortel

  • 1Department of Obstetrics and Gynecology, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.

Cancer Metastasis Reviews
|January 1, 1987
PubMed

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...