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Maternal COVID-19 vaccine acceptance among Malaysian pregnant women: A multicenter cross-sectional study
Aida Kalok1, Wira Razak Dali1, Shalisah Sharip2
1Department of Obstetrics and Gynaecology, Faculty of Medicine, National University of Malaysia, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Insights
Maternal vaccine acceptance for COVID-19 was 77.1% in Malaysian pregnant women. Factors like income, employment, and reliable information sources influenced acceptance, highlighting the need for professional guidance to reduce hesitancy.
Area of Science:
- Public Health
- Epidemiology
- Vaccinology
Background:
- The COVID-19 pandemic significantly impacted global health and economies.
- Pregnant women face increased risks for severe COVID-19 complications due to physiological changes.
- Assessing vaccine acceptance among pregnant populations is crucial for public health strategies.
Purpose of the Study:
- To evaluate the acceptance rate of the COVID-19 vaccine among pregnant women in Malaysia.
- To identify factors influencing maternal vaccine acceptance and hesitancy.
Main Methods:
- A multi-center survey was conducted in four teaching hospitals in Klang Valley, Malaysia.
- Self-administered electronic questionnaires assessed perceptions, attitudes, and anxiety related to COVID-19 vaccination.
- Data from 1,272 pregnant women were analyzed.
Main Results:
- Maternal vaccine acceptance for COVID-19 was 77.1%.
- Positive predictors included higher income, employment, being a health sector worker, personal/social infection history, and pregnancy-related anxiety.
- Reliance on internet/social media for information correlated with higher acceptance.
Conclusions:
- High maternal vaccine acceptance in urban Malaysian pregnant women may be linked to socio-economic status.
- Responsible use of online information and professional health counseling are key to addressing vaccine hesitancy.
Introduction:
The coronavirus disease 2019 (COVID-19) caused a global pandemic that resulted in devastating health, economic and social disruption. Pregnant mothers are susceptible to COVID-19 complications due to physiological and immunity changes in pregnancy. We aimed to assess the maternal vaccine acceptance of the COVID-19 vaccine.
Methods:
A multi-center study across four teaching hospitals in the Klang Valley, Malaysia was conducted between September 2021 and May 2022. A survey was conducted using a self-administered electronic questionnaire. The survey instruments included; (1) maternal perception and attitude toward COVID-19 vaccination, (2) COVID-19 pregnancy-related anxiety, and 3) generalized anxiety disorder.
Results:
The response rate was 96.6%, with a final number for analysis of 1,272. The majority of our women were Malays (89.5%), with a mean age (standard deviation, SD) of 32.2 (4.6). The maternal vaccine acceptance in our study was 77.1%. Household income (p < 0.001), employment status (p = 0.011), and health sector worker (p = 0.001) were independent predictors of maternal willingness to be vaccinated. COVID-19 infection to self or among social contact and greater COVID-19 pregnancy-related anxiety were associated with increased odds of accepting the SARS-CoV-2 vaccine. Women who rely on the internet and social media as a source of vaccine information were more likely to be receptive to vaccination (adjusted odd ratio, AOR 1.63; 95% CI 1.14-2.33). Strong correlations were observed between maternal vaccine acceptance and the positive perception of (1) vaccine information (p < 0.001), (2) protective effects of vaccine (p < 0.001), and (3) getting vaccinated as a societal responsibility (p < 0.001).
Discussion:
The high maternal vaccine acceptance rate among urban pregnant women in Malaysia is most likely related to their high socio-economic status. Responsible use of the internet and social media, alongside appropriate counseling by health professionals, is essential in reducing vaccine hesitancy among pregnant women.
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