Related Experiment Video
Updated: Aug 7, 2025

08:59
T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
Published on: January 12, 2021
8.3K
TCR sequencing: applications in immuno-oncology research
Á F Sanromán1, K Joshi2,3, L Au1,4,5,6
1Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.
Immuno-Oncology Technology
|March 13, 2023
Abstract:
•T-cell receptor (TCR) interaction with major histocompatibility complex-antigen complexes leads to antitumour responses.•TCR sequencing analysis allows characterisation of T cells that recognise tumour neoantigens.•T-cell clonal revival and clonal replacement potentially underpin immunotherapy responses.

