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Updated: Aug 7, 2025

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Recent developments in modeling, imaging, and monitoring of cardiovascular diseases using machine learning
Hamed Moradi1, Akram Al-Hourani2, Gianmarco Concilia2
1Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands.
Abstract:
Cardiovascular diseases are the leading cause of mortality, morbidity, and hospitalization around the world. Recent technological advances have facilitated analyzing, visualizing, and monitoring cardiovascular diseases using emerging computational fluid dynamics, blood flow imaging, and wearable sensing technologies. Yet, computational cost, limited spatiotemporal resolution, and obstacles for thorough data analysis have hindered the utility of such techniques to curb cardiovascular diseases. We herein discuss how leveraging machine learning techniques, and in particular deep learning methods, could overcome these limitations and offer promise for translation. We discuss the remarkable capacity of recently developed machine learning techniques to accelerate flow modeling, enhance the resolution while reduce the noise and scanning time of current blood flow imaging techniques, and accurate detection of cardiovascular diseases using a plethora of data collected by wearable sensors.
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