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Leaky Scanning

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA. Marilyn Kozak discovered that the sequence RCCAUGG (where R...

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Related Experiment Video

Updated: Aug 7, 2025

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

Corrigendum: The Vacc-SeqQC project: Benchmarking RNA-Seq for clinical vaccine studies.

Johannes B Goll¹, Steven E Bosinger^2,3,4,5, Travis L Jensen¹

¹Department of Biomedical Data Science and Bioinformatics, The Emmes Company, LLC, Rockville, MD, United States.

Frontiers in Immunology

|March 13, 2023

Summary

This study corrects a previous article DOI. Please refer to the updated DOI for accurate citation and access to the research findings.

Keywords:

ERCC RNA-Seq gene filtering read length reproducibility sequencing depth statistical power tularemia vaccine (DVC-LVS)

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Last Updated: Aug 7, 2025

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

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Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

Published on: September 13, 2018

Area of Science:

Immunology
Molecular Biology

Context:

Correction of a previously published article DOI.
Ensuring accurate citation and access to scientific literature.

Purpose:

To provide the correct article DOI for the publication.
To facilitate proper referencing and retrieval of research.

Summary:

The article DOI has been updated to 10.3389/fimmu.2022.1093242.
This correction ensures readers can access the intended research.

Impact:

Improved accuracy in scientific referencing.
Enhanced discoverability of the corrected research article.