Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis

Lindsay A Lo1, April Christiansen2, Lauren Eadie3

  • 1Department of Public Health Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

Summary

Cannabidiol (CBD) use is linked to higher rates of liver enzyme elevation and drug-induced liver injury (DILI). High doses and certain medications increase risk, but severe cases are rare, especially at lower CBD doses.