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Updated: Aug 7, 2025
Culturing and Maintaining Clostridium difficile in an Anaerobic Environment
Published on: September 14, 2013
Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow
Kelly A Reagan1, David M Chan1, Ginger Vanhoozer2
1Department of Mathematics and Applied Mathematics, Virginia Commonwealth University, Richmond, Virginia.
Objective:
To model the effects of active detection and isolation (ADI) regarding Clostridioides difficile infection (CDI) in the bone marrow transplant (BMT) unit of our hospital.
Setting:
ADI was implemented in a 21-patient bone marrow unit.
Patients:
Patients were bone marrow recipients on this unit.
Interventions:
We compared active ADI, in which patients who tested positive for colonization of C. difficile before their hospital stay were placed under extra contact precautions, with cases not under ADI.
Results:
Within the BMT unit, ADI reduced total cases of CDI by 24.5% per year and reduced hospital-acquired cases by ∼84%. The results from our simulations also suggest that ADI can save ∼$67,600 per year in healthcare costs.
Conclusions:
Institutions with active BMT units should consider implementing ADI.
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14:43Differentiating Functional Roles of Gene Expression from Immune and Non-immune Cells in Mouse Colitis by Bone Marrow Transplantation
Published on: October 1, 2012
09:12A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
Published on: June 15, 2018
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