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Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications

Published on: August 4, 2018

Recent Development of Polyhydroxyalkanoates (PHA)-Based Materials for Antibacterial Applications: A Review.

Safa Ladhari^1,2, Nhu-Nang Vu^1,2, Cédrik Boisvert^1,2

¹Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières (UQTR), 3351 Boulevard des Forges, Trois-Rivières, Québec G8Z 4M3, Canada.

ACS Applied Bio Materials

|March 13, 2023

Summary

Polyhydroxyalkanoates (PHAs) are emerging as green, biodegradable materials for combating bacterial infections. This review critically examines PHA biopolymers for antibacterial applications, production, and future research directions.

Keywords:

antibacterial biocompatibility nanomaterials polyhydroxyalkanoates therapeutic agents

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Area of Science:

Biomaterials Science
Polymer Chemistry
Microbiology

Background:

Antimicrobial resistance is a critical global health threat, necessitating novel solutions.
Bactericidal materials offer a promising strategy to combat pathogenic bacteria.
Polyhydroxyalkanoates (PHAs) are gaining attention as sustainable, biodegradable materials for healthcare.

Approach:

This review systematically analyzes recent advancements in polyhydroxyalkanoates (PHAs) for antibacterial applications.
It explores cutting-edge production technologies and potential application fields for PHA biopolymers.
The review also focuses on incorporating antibacterial agents into PHA materials for enhanced protection.

Key Points:

PHAs exhibit potential for developing effective antibacterial materials.
Integrating specific antibacterial agents can improve the efficacy and durability of PHA-based antimicrobial solutions.
Current research highlights the need for further investigation into PHA properties and applications.

Conclusions:

Polyhydroxyalkanoates represent a promising class of biopolymers for developing next-generation antibacterial materials.
Further research is essential to fully realize the potential of PHAs in combating microbial pathogens and addressing antimicrobial resistance.
This review identifies research gaps and proposes future perspectives for PHA-based antibacterial innovations.