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Validity of ICD codes to identify do-not-resuscitate orders among older adults with heart failure: A single center
Katherine Callahan1, Yubraj Acharya1, Christopher S Hollenbeak1
1Department of Health Policy and Administration, College of Health and Human Development, The Pennsylvania State University, University Park, Williamsport, Pennsylvania, United States of America.
Insights
International Classification of Disease (ICD) codes for do-not-resuscitate (DNR) orders are valid proxies for DNR status in electronic medical records for older heart failure patients. This finding aids advance care planning research using large datasets.
Area of Science:
- Health Services Research
- Medical Informatics
- Geriatric Medicine
Background:
- Advance care planning (ACP) research is hindered by limited data on ACP variables in large datasets.
- Electronic medical records (EMR) often lack easily accessible data on critical care decisions.
- Do-not-resuscitate (DNR) orders are a key component of advance care planning.
Purpose of the Study:
- To validate International Classification of Disease (ICD) codes as proxies for DNR orders.
- To assess the accuracy of ICD codes against EMR documentation of DNR orders.
- To determine the utility of billing codes for identifying DNR status in research.
Main Methods:
- Study included 5,016 older adults (age >65) with heart failure.
- DNR orders were identified using ICD-9/ICD-10 codes and manual EMR review.
- Statistical measures included sensitivity, specificity, predictive values, and agreement (kappa).
Main Results:
- ICD codes demonstrated high accuracy: 84.6% sensitivity, 96.6% specificity.
- Positive predictive value was 90.5%, and negative predictive value was 94.3%.
- A high kappa statistic (0.83) indicated substantial agreement, despite some systematic disagreement.
Conclusions:
- ICD codes serve as a reliable proxy for DNR orders in hospitalized heart failure patients.
- This validates the use of billing data for advance care planning research.
- Further studies are needed to confirm generalizability to other patient populations.
Background:
Observational research on the advance care planning (ACP) process is limited by a lack of easily accessible ACP variables in many large datasets. The objective of this study was to determine whether International Classification of Disease (ICD) codes for do-not-resuscitate (DNR) orders are valid proxies for the presence of a DNR recorded in the electronic medical record (EMR).
Methods:
We studied 5,016 patients over the age of 65 who were admitted to a large, mid-Atlantic medical center with a primary diagnosis of heart failure. DNR orders were identified in billing records from ICD-9 and ICD-10 codes. DNR orders were also identified in the EMR by a manual search of physician notes. Sensitivity, specificity, positive predictive value and negative predictive value were calculated as well as measures of agreement and disagreement. In addition, estimates of associations with mortality and costs were calculated using the DNR documented in EMR and the DNR proxy identified in ICD codes.
Results:
Relative to the gold standard of the EMR, DNR orders identified in ICD codes had an estimated sensitivity of 84.6%, specificity of 96.6%, positive predictive value of 90.5%, and negative predictive value of 94.3%. The estimated kappa statistic was 0.83, although McNemar's test suggested there was some systematic disagreement between the DNR from ICD codes and the EMR.
Conclusions:
ICD codes appear to provide a reasonable proxy for DNR orders among hospitalized older adults with heart failure. Further research is necessary to determine if billing codes can identify DNR orders in other populations.
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