Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anatomy of the Intestines01:23

Anatomy of the Intestines

72.8K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.8K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

381
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
381
Transcytosis of IgG01:15

Transcytosis of IgG

2.8K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.8K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

340
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
340

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interdisciplinary training on noncommunicable diseases and sustained change in primary health care in the context of health reform, COVID-19, and war in Ukraine: A repeated qualitative study, 2016-2022.

BMC public health·2026
Same author

Usual nutrient intake and adherence to dietary reference values among 3-6-year-old Finnish preschoolers.

Food & nutrition research·2026
Same author

Perceived barriers to adopting more plant-based diets across sociodemographic groups: findings from a population-based survey in Finland.

Journal of nutritional science·2026
Same author

Physical Activity Since Childhood and its Association qith Changes in Midlife Cognitive Functions: A Longitudinal Prospective Cohort Study.

Medicine and science in sports and exercise·2026
Same author

Assessing the progress in implementing population-based policies to reduce the burden of noncommunicable diseases in Eastern Europe and Central Asia, 2010-2024.

Health policy and planning·2026
Same author

Blood donor biobank pipeline to collect genome-based samples for research.

Scientific reports·2026

Related Experiment Video

Updated: Aug 7, 2025

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

3.8K

Infant Feeding, Gut Permeability, and Gut Inflammation Markers.

Katariina Koivusaari1,2, Sari Niinistö1, Jaakko Nevalainen3

  • 1From the Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.

Journal of Pediatric Gastroenterology and Nutrition
|March 13, 2023
PubMed
Summary

Infant diets impact gut health. While breast milk may increase a marker of inflammation, complementary foods like fruits and vegetables can reduce gut permeability and inflammation markers in infants.

More Related Videos

Assessment of Gut Barrier Integrity in Mice Using Fluorescein-Isothiocyanate-Labeled Dextran
05:14

Assessment of Gut Barrier Integrity in Mice Using Fluorescein-Isothiocyanate-Labeled Dextran

Published on: November 18, 2022

8.9K
Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

2.3K

Related Experiment Videos

Last Updated: Aug 7, 2025

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

3.8K
Assessment of Gut Barrier Integrity in Mice Using Fluorescein-Isothiocyanate-Labeled Dextran
05:14

Assessment of Gut Barrier Integrity in Mice Using Fluorescein-Isothiocyanate-Labeled Dextran

Published on: November 18, 2022

8.9K
Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

2.3K

Area of Science:

  • Pediatric Nutrition
  • Gastroenterology
  • Immunology

Background:

  • Gut permeability and inflammation are implicated in type 1 diabetes development.
  • The role of infant diet in modulating these gut mechanisms is not well understood.

Purpose of the Study:

  • To investigate the association between breast milk and other food intake with gut inflammation markers and permeability in infants.
  • To explore how dietary patterns in the first year of life influence gut health indicators.

Main Methods:

  • Longitudinal study of 73 infants from birth to 12 months.
  • Dietary intake assessed via questionnaires and food records.
  • Gut permeability measured using lactulose/mannitol test; fecal calprotectin and HBD-2 analyzed.

Main Results:

  • Gut permeability and inflammation markers decreased over the first year.
  • Hydrolyzed infant formula, fruits, and juices associated with lower intestinal permeability.
  • Fruits, juices, vegetables, and oats linked to lower HBD-2.
  • Breast milk intake correlated with higher fecal calprotectin; fruits, juices, vegetables, and potatoes linked to lower calprotectin.

Conclusions:

  • Higher breast milk intake may be associated with increased calprotectin.
  • Complementary foods, including fruits, vegetables, and oats, show potential in reducing gut permeability and inflammation markers in infants.