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Updated: Aug 7, 2025

Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
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Caffeine: benefits and drawbacks for technical performance.

D Parry1, S Iqbal2, I Harrap3

  • 1Department of Anatomy, King's College London, Hodgkin Building, London SE1 1UI, UK.

The British Journal of Oral & Maxillofacial Surgery
|March 13, 2023
PubMed
Summary
This summary is machine-generated.

Surgeons experiencing sleep deprivation may use caffeine to combat fatigue, but this stimulant can negatively impact their cognitive and physical performance, potentially affecting patient outcomes.

Keywords:
CaffeineHuman factorsPatient carePerformanceWellbeing

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Area of Science:

  • Medical Science
  • Surgical Procedures
  • Occupational Health

Background:

  • High-stakes surgical and minimally-invasive procedures demand peak performance.
  • Surgeons face increasing demands and disrupted sleep patterns, leading to fatigue.
  • Sleep deprivation negatively impacts surgeon health and clinical outcomes.

Purpose of the Study:

  • To review the evidence on caffeine use by surgeons.
  • To assess the consequences of caffeine on technical performance.
  • To evaluate the impact of caffeine on clinical outcomes.

Main Methods:

  • Literature review of studies on caffeine, surgical performance, and clinical outcomes.
  • Analysis of research investigating stimulant effects on cognitive and physical function.
  • Synthesis of evidence regarding caffeine's benefits versus risks in surgical settings.

Main Results:

  • Caffeine is used by some surgeons to mitigate fatigue.
  • Stimulant use, including caffeine, may impair cognitive and physical function.
  • Evidence is needed to clarify caffeine's net effect on surgical performance and patient safety.

Conclusions:

  • The use of caffeine by surgeons to manage fatigue requires careful consideration.
  • Potential negative effects of caffeine on performance must be weighed against perceived benefits.
  • Further research is necessary to guide safe stimulant use in surgical professionals.