Related Experiment Video
Updated: Aug 7, 2025

19:15
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
86.2K
The Neonatal Withdrawal Assessment Tool (NWAT): pilot inter-rater reliability and content validity
Gonca Bektas1, Taylor Soderborg1, Cheryl Slater2
1Boston Combined Residency Program in Pediatrics, Boston Medical Center and Boston Children's Hospital, Boston, MA, USA.
Summary
A new tool, the Neonatal Withdrawal Assessment Tool (NWAT), shows high reliability for assessing opioid withdrawal in preterm infants. This pilot study suggests NWAT is a promising instrument for NICU clinical practice.
Area of Science:
- Neonatalogy
- Pharmacology
- Clinical Assessment Tools
Background:
- Iatrogenic opioid withdrawal is a significant concern in preterm infants within the Neonatal Intensive Care Unit (NICU).
- Currently, no validated tool exists to systematically assess this condition in this vulnerable population.
Purpose of the Study:
- To develop and pilot test the Neonatal Withdrawal Assessment Tool (NWAT) for assessing iatrogenic opioid withdrawal in preterm infants.
- To evaluate the inter-rater reliability (IRR) and content validity of the NWAT.
Main Methods:
- Fifty-one NICU providers assessed standardized simulated cases.
- Twenty paired provider assessments were conducted on five preterm infants.
- A survey was administered to providers to assess the content validity of the NWAT.
Main Results:
- The NWAT demonstrated high inter-rater reliability, with 95.6% agreement on simulated cases and 98.8% agreement on pilot infants.
- Provider surveys indicated strong agreement that the NWAT adequately measures withdrawal symptoms in critically ill infants.
- The tool showed high content validity in this pilot study.
Conclusions:
- The Neonatal Withdrawal Assessment Tool (NWAT) shows promising high inter-rater reliability and content validity for assessing iatrogenic opioid withdrawal in preterm infants.
- Further research with larger, diverse patient populations is recommended before widespread clinical adoption of the NWAT.
Related Concept Videos
Reliability and Validity
12.8K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
12.8K
McNemar's Test
339
McNemar's Test is a nonparametric statistical test used to determine if there is a significant difference in proportions between two related groups when the outcome is binary (e.g., yes/no, success/failure). It is beneficial when we have paired data, such as pre-test/post-test designs, where the same subjects are measured under two different conditions. The test is named after the statistician Quinn McNemar, who introduced it in 1947. It is commonly used in situations where subjects are...
339
Kendall's Coefficient of Concordance
451
Kendall's Coefficient of Concordance (W), also known as Kendall's W, is a non-parametric statistical measure used to assess the agreement or concordance between multiple raters or judges when they rank a set of items. It is often used when you have ordinal data (ranks) and you want to see if there is consistency or consensus among the raters. It is widely applied in research areas such as psychology, medicine, and social sciences, where multiple judges are asked to rank or rate subjects...
451

