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Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
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Traumatic Injury in Pregnancy: A Propensity Score-Matched Analysis
Ayman Ali1, John T Simpson1, Danielle Tatum1
1Tulane University School of Medicine, Department of Surgery, New Orleans, Louisiana.
The Journal of Surgical Research
|March 14, 2023
Summary
Traumatically injured pregnant patients (PPs) did not experience higher mortality or complications than nonpregnant controls. However, PPs showed increased assault victim rates, longer hospital stays, and higher intensive care unit (ICU) admission rates.
Area of Science:
- Trauma Surgery
- Maternal Health
- Emergency Medicine
Background:
- Trauma is a leading cause of nonobstetrical maternal death.
- In-hospital outcomes for acutely injured pregnant patients (PPs) compared to nonpregnant control groups (CGs) are not well-described.
- A hypothesis posited worse outcomes for PPs after acute trauma.
Purpose of the Study:
- To compare in-hospital outcomes of traumatically injured pregnant patients (PPs) with similarly aged nonpregnant control groups (CGs).
- To identify differences in mortality, disposition, length of stay (LOS), and complications between PPs and CGs.
Main Methods:
- Utilized the American College of Surgeons Trauma Quality Improvement Program (TQIP) database from 2017-2019.
- Employed propensity score matching based on age, race, injury severity score, and trauma type to create comparable PP and CG cohorts.
- Primary outcomes analyzed included mortality, disposition, LOS, and complication rates.
Main Results:
- A total of 1078 traumatically injured pregnant females were identified, with 990 patients in the matched PP and CG cohorts.
- Pregnant patients were more likely to be assault victims (11% vs. 6%) and had longer LOS (5 days vs. 3 days).
- PPs showed higher rates of mechanical ventilation (26% vs. 16%), ICU admission (44% vs. 32%), and direct OR transfer (34% vs. 15%), with similar complication and mortality rates.
Conclusions:
- Acutely injured pregnant patients do not have increased mortality or complications compared to matched nonpregnant controls.
- Pregnant patients are more likely to be assault victims, require mechanical ventilation or ICU admission, and experience longer hospital stays after trauma.
- Outcomes such as emergency department discharge were less frequent in pregnant patients.
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