Related Experiment Video

Updated: Aug 7, 2025

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
07:59

Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration

Published on: April 4, 2022

1.4K

Management of Stable Angina in the Older Adult Population

Michael G Nanna1,2, Stephen Y Wang2, Abdulla A Damluji3,4

  • 1Section of Cardiovascular Medicine (M.G.N.), Yale School of Medicine, New Haven, CT.

Circulation. Cardiovascular Interventions
|March 14, 2023
PubMed

Insights

Older adults face higher risks from stable ischemic heart disease and angina. Management requires personalized care, focusing on patient priorities and shared decision-making for better outcomes.

Area of Science:

  • Gerontology
  • Cardiology
  • Clinical Medicine

Background:

  • Aging populations are increasing the prevalence of stable ischemic heart disease (SIHD).
  • Older adults experience disproportionately higher morbidity and mortality from stable angina.
  • Limited evidence exists for SIHD management in older adults due to trial underrepresentation.

Purpose of the Study:

  • To review definitions of aging in the context of SIHD.
  • To assess the clinical burden and presentation of SIHD in older patients.
  • To evaluate evidence for SIHD treatments and propose a decision-making framework for this demographic.

Main Methods:

  • Literature review of aging definitions and SIHD in older adults.
  • Analysis of subgroup data from SIHD trials and observational studies.
  • Synthesis of evidence for medical therapy and revascularization in elderly patients.

Main Results:

  • Older adults present unique challenges in SIHD management due to comorbidities and treatment risks.
  • Current SIHD guidelines lack specific evidence for the elderly population.
  • Patient-centered goals of care are crucial for treatment decisions.

Conclusions:

  • Management of stable angina in older adults necessitates a personalized approach.
  • Reassessing patient priorities and preferences is paramount.
  • Future research should focus on representative elderly populations and patient-centered outcomes.

Keywords:
agedagingangina, stablecoronary artery diseasemorbiditypercutaneous coronary intervention

More Related Videos

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.3K
Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders05:58

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders

Published on: February 3, 2021

3.6K

Related Concept Videos

Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
12
Angina V: Nursing Management01:20

Angina V: Nursing Management

Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
23
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
13
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
16
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
16
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
19