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Updated: Aug 7, 2025
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Identification of Circular RNAs using RNA Sequencing
Published on: November 14, 2019
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Challenges and opportunities for circRNA identification and delivery
Jiani Dong1, Zhuoer Zeng1,2, Ying Huang1
1Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, China.
Critical Reviews in Biochemistry and Molecular Biology
|March 14, 2023
Summary
Circular RNAs (circRNAs) are vital noncoding RNAs with therapeutic potential. This review covers circRNA detection methods and delivery strategies for research and clinical applications.
Area of Science:
- Molecular Biology
- Genetics
- Biochemistry
Background:
- Circular RNAs (circRNAs) are conserved noncoding RNAs with tissue-specific expression.
- circRNAs possess unique cellular functions and potential as biomarkers.
- Accurate detection and precise regulation of circRNAs are crucial for research and therapeutics.
Conclusions:
- Advanced circRNA detection and delivery systems are essential for understanding biological roles and disease association.
- Further research is needed to overcome challenges in circRNA analysis and therapeutic applications.
- circRNAs hold significant promise as biomarkers and therapeutic targets.
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