Nanographite-assisted matrix solid phase dispersion microextraction of active and toxic compounds from complex food...

Area of Science:

• Analytical Chemistry
• Environmental Science
• Food Science

Background:

• Simultaneous extraction of active and toxic compounds from complex food matrices remains challenging.
• Developing environmentally friendly analytical methods is crucial for food safety and quality assessment.
• Nanomaterials offer unique properties for enhancing extraction efficiency in complex samples.

Purpose of the Study:

• To develop and optimize a novel nanographite-assisted matrix solid phase dispersion microextraction (NG-MSPDM) method.
• To achieve simultaneous extraction of target analytes from food matrices using an eco-friendly eluent.
• To validate the method's performance for accuracy, reproducibility, and recovery.

Main Methods:

• Optimization of NG-MSPDM using single-factor experiments and response surface methodology.
• Utilized cyclodextrin aqueous solution as an environmentally friendly eluent.
• Employed ion mobility quadrupole time-of-flight mass spectrometry (IM-Q-TOF/MS) for analyte identification and quantification.

Main Results:

• Achieved excellent linearity (R² ≥ 0.9909) in the range of 0.10-20 μg/mL.
• Obtained low limits of detection (< 52.01 ng/mL) and satisfactory reproducibility (< 3.21%).
• Demonstrated successful simultaneous extraction of flavonoids and phenoxyacetic herbicides from Alpinia officinarum.

Conclusions:

• The developed NG-MSPDM method is effective and efficient for the simultaneous extraction of diverse compounds from food matrices.
• The use of nanographite and cyclodextrin offers an environmentally sustainable approach to sample preparation.
• The method provides reliable quantitative data for complex food analysis.