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The role of a multicentre data repository in ocular inflammation: The Ocular Autoimmune Systemic Inflammatory
Sean Ming Sheng Ng1, Rebecca Low2, Clara Pak3
1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Eye (London, England)
|March 15, 2023
Summary
The Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) registry collects global data on ocular inflammation. This comprehensive dataset aims to advance uveitis research and develop new diagnostic and treatment guidelines.
Area of Science:
- Ophthalmology
- Rheumatology
- Immunology
Background:
- Limited multi-continental data exists for ocular inflammation and uveitis.
- Existing registries are often fragmented, disease-specific, or administrative.
- Robust data is needed for epidemiological studies and prognostication in uveitis.
Purpose of the Study:
- To establish the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) Clinical Registry.
- To collect prospective and retrospective data on diverse ocular inflammatory conditions globally.
- To create a comprehensive, structured dataset for uveitis research.
Main Methods:
- A global, web-based platform with offline access.
- Collection of demographics, medical history, clinical presentation, diagnosis, and visual outcomes.
- Inclusion of clinical imaging data (OCT, FA, ICGA).
Main Results:
- OASIS captures diverse, well-structured, and clinically meaningful data.
- The registry facilitates simplified and consistent data collection.
- A comprehensive dataset is now available for analysis.
Conclusions:
- OASIS provides a robust international dataset for ocular inflammation research.
- Applications include epidemiological analysis, drug safety monitoring, and treatment efficacy studies.
- Data will inform new classification, diagnostic, and treatment guidelines for uveitis.
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