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Published on: June 2, 2014
Prevalence, clinical characteristics and associated factors of cardiac cephalalgia: A prospective study
María Pilar Navarro-Pérez1,2, Judit Espinosa-Rueda1,2, Sara Ballesta-Martínez1,2
1Neurology Department, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
Insights
Cardiac cephalalgia affects 14.2% of patients with suspected acute coronary syndrome. This study details its features, suggesting a need to revise diagnostic criteria for this heart-related headache.
Area of Science:
- Cardiology
- Neurology
- Clinical Research
Background:
- Cardiac cephalalgia prevalence and clinical features are poorly understood.
- Limited data exists on associated factors for this specific headache type.
Purpose of the Study:
- To determine the prevalence of cardiac cephalalgia.
- To describe its clinical characteristics.
- To identify associated factors in patients with suspected acute coronary syndrome.
Main Methods:
- Prospective study of 438 patients admitted for suspected acute coronary syndrome.
- Standardized interviews within 24 hours of admission.
- Assessment of headache in relation to acute coronary syndrome and its characteristics.
Main Results:
- Prevalence of cardiac cephalalgia was 14.2% (54/381) in patients with confirmed myocardial ischemia.
- Common features include frontal location, pressing quality, and moderate intensity.
- Pain referred to jaws, palpitations, and circumflex artery involvement were associated with cardiac cephalalgia; hypertension was inversely associated.
Conclusions:
- Cardiac cephalalgia prevalence is 14.2%.
- Findings provide valuable insights into cardiac cephalalgia characteristics.
- Current diagnostic criteria for cardiac cephalalgia may require revision.
Background:
The prevalence of cardiac cephalalgia is unknown and there is limited information about its clinical features. We aimed to assess the prevalence of cardiac cephalalgia, its clinical characteristics and associated factors.
Methods:
We conducted a prospective study of patients with suspected acute coronary syndrome admitted to the Cardiology Service at Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain, over a one-year period. We interviewed patients within the first 24 hours of admission using a standardized case-report form to assess the presence of headache in relation to the acute coronary syndrome and its characteristics.
Results:
We included 438 patients, 381 with confirmed myocardial ischemia. Prevalence of cardiac cephalalgia was 14.2% (n = 54). The most common features were frontal location, pressing quality and moderate intensity. Pain referred to the jaws (aOR 2.61; 95% CI 1.33-5.12; p = 0.005), palpitations (aOR 3.65; 95% CI 1.57-8.50; p = 0.003) and circumflex coronary artery as the culprit artery for the myocardial ischemia (aOR 3.8; 95% CI 1.07-13.74; p = 0.021) were related to cardiac whereas history of hypertension was inversely associated (aOR 0.37: 95% CI 0.18-0.74; p = 0.005).
Conclusion:
The prevalence of cardiac cephalalgia was 14.2%. Our study provides valuable information about cardiac cephalalgia characteristics that suggest revision of current diagnostic criteria.
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