Related Experiment Video
Updated: Aug 6, 2025
Injection of dsRNA into Female A. aegypti Mosquitos
Published on: July 4, 2007
Short-term Side Effects of mRNA-based COVID-19 Vaccine Among Jordanian Population; a Cross-sectional Study
1Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman, Jordan.
Introduction:
One type of the developed COVID-19 vaccines that received emergency permission and was approved by the food and drug administration (FDA) is the mRNA-based vaccine. The aim of this study is to gather information on the Jordanian population's experience with the vaccine's side effects.
Methods:
The study objectives were addressed through a cross-sectional study, which collected information regarding the short-term side effects experienced by the vaccinated individuals within one month following the injection of an mRNA-based COVID-19 vaccine. Data collection was carried out in August 2021. Participants were invited to take part in a self-administered web-based survey created using Google Forms.
Results:
Among the study's participants (n= 533), about 56% experienced side effects after the first dose of the mRNA-based COVID-19 vaccine. The most commonly reported side effects after the first dose were sore arm at the injection site (91.6%), and fatigue (83.06%). The female gender was significantly associated with experiencing fatigue, discomfort, chills, and hair loss. Being over 30 years old was significantly associated with experiencing cough. Being a smoker was significantly associated with experiencing shortness of breath and gastrointestinal symptoms.
Conclusion:
The mRNA-based COVID-19 vaccine side effects were common, yet, mild, local, and self-limited. The local pain at the injection site was the most commonly reported side effect. Hopefully, the study's findings will aid in lowering resistance to vaccination.
Insights
Most individuals receiving mRNA COVID-19 vaccines reported mild side effects like sore arm and fatigue. These common, short-term effects were generally not severe, potentially easing vaccine hesitancy.
Area of Science:
- Vaccinology
- Public Health
- Immunology
Background:
- mRNA COVID-19 vaccines are widely used and approved by regulatory bodies like the FDA.
- Understanding vaccine side effects is crucial for public acceptance and vaccine programs.
Purpose of the Study:
- To investigate the short-term side effects of mRNA COVID-19 vaccines in the Jordanian population.
- To identify common adverse events and associated demographic factors.
Main Methods:
- A cross-sectional study was conducted using a web-based survey.
- Data on side effects within one month post-vaccination were collected from 533 participants.
- The survey was self-administered via Google Forms.
Main Results:
- Approximately 56% of participants reported side effects after the first mRNA vaccine dose.
- The most frequent side effects were injection site pain (sore arm) and fatigue.
- Female gender, age over 30, and smoking status were associated with specific side effects.
Conclusions:
- Side effects from mRNA COVID-19 vaccines are common but typically mild, local, and self-limiting.
- Injection site pain is the most prevalent side effect.
- Findings may help reduce vaccine hesitancy.
Related Concept Videos
01:12Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
01:21Skeletal Muscle Relaxants: Adverse Effects
Unlike...
01:51Vaccinations
01:30Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
02:59Biological Effects of Radiation
02:06Allergic Reactions