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Psychosurgery

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Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Treatment Strategies for Psychological Disorders

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Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
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Depression: Overview01:18

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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Depressive Disorders: MDD and Dysthymia

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Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
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Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
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[A Surgically Treated Depression].

Valentina Vigaru1, Dominik Müntener2, Jan Kuchynka1

  • 11 Klinik für Geriatrie, Rheumatologie und Rehabilitation, Kantonsspital Schaffhausen, Schaffhausen, Schweiz.

Praxis
|March 15, 2023
PubMed
Summary
This summary is machine-generated.

A cerebellar tumor and hydrocephalus were discovered in a patient with worsening depression, leading to a diagnosis of Von Hippel-Lindau (VHL) syndrome. Family screening is recommended for VHL syndrome unless genetic testing excludes the disease.

Area of Science:

  • Neurology
  • Oncology
  • Genetics

Background:

  • Depression can manifest with unclear symptoms and may mask underlying neurological conditions.
  • Von Hippel-Lindau (VHL) syndrome is a genetic disorder predisposing individuals to various tumors.
Keywords:
DepressionHydrocephalus obstructivusHämangioblastomVon-Hippel-Lindau syndromeVon-Hippel-Lindau-Syndromhemangioblastomahydrocephalus obstructivus

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