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Updated: Aug 6, 2025

Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization

Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization

Published on: April 19, 2015

Reconfigurable scaffolds for adaptive tissue regeneration.

Mingxing Peng^1,2, Qilong Zhao¹, Min Wang³

¹Institute of Biomedical & Health Engineering, Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen, 518055, China. ql.zhao@siat.ac.cn.

|March 15, 2023

Summary

Reconfigurable scaffolds offer adaptive solutions for tissue engineering by changing shape to better integrate with tissues and cells. This technology promises improved tissue regeneration and clinical treatments.

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Last Updated: Aug 6, 2025

Electrospun Nanofiber Scaffolds with Gradations in Fiber Organization

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Published on: April 19, 2015

A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

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Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

Area of Science:

Biomaterials Science
Tissue Engineering
Regenerative Medicine

Background:

Conventional scaffolds face challenges in adapting to complex 3D tissue shapes and mimicking native cell microenvironments.
Tissue engineering and regenerative medicine utilize scaffold-based strategies for treating tissue damage and disease.

Purpose of the Study:

To provide an overview of reconfigurable scaffolds in adaptive tissue regeneration.
To summarize materials used in reconfigurable scaffolds and their applications.
To discuss challenges and future prospects of reconfigurable scaffolds.

Main Methods:

Review of cutting-edge research on reconfigurable scaffolds.
Summary of materials enabling scaffold reconfigurability.
Highlighting applications in adaptive tissue regeneration.

Main Results:

Reconfigurable scaffolds demonstrate potential in overcoming bio-adaptation challenges in tissue engineering.
Advances in "intelligent" biomaterials are driving the development of reconfigurable scaffolds.
These scaffolds can alter macro-shapes and/or micro-structures for improved tissue integration.

Conclusions:

Reconfigurable scaffolds show great promise for adaptive tissue regeneration.
Further research into challenges and prospects will illuminate the future of next-generation scaffolds.
Upgrading adaptability is key for future reconfigurable scaffold development.