Long-term success for people living with HIV: A framework to guide practice

Area of Science:

• HIV/AIDS research
• Public health
• Patient-centered care

Background:

• People living with HIV (PLWH) have increased life expectancy, necessitating updated definitions of long-term success.
• Current strategies require evolution to address the complex, multifaceted needs of PLWH.
• A revised framework is crucial for holistic, long-term well-being.

Purpose of the Study:

• To develop a new definition and framework for Long-Term Success (LTS) for people living with HIV.
• To create a comprehensive, person-centric approach to guide care and support for PLWH.
• To establish measurable outcomes for improved long-term health and quality of life.

Main Methods:

• A two-phase research program was conducted to understand the experiences of PLWH.
• Expert-led workshops were utilized to refine insights and develop the LTS framework.
• The framework was built upon identified themes from participant experiences.

Main Results:

• The LTS framework comprises five key outcome pillars: sustained undetectable viral load, minimal treatment impact, optimized quality of life, integrated healthcare, and freedom from stigma.
• Supporting statements were developed to aid in achieving each LTS pillar.
• The framework provides a structured approach to defining and measuring long-term success.

Conclusions:

• The developed LTS framework offers a comprehensive, person-centric approach for improving long-term well-being in PLWH.
• Achieving the LTS pillars can significantly enhance the lives of individuals living with HIV.
• The framework supports the vision of enabling every person living with HIV to live their best life.