DTI of the Olfactory Bulb in COVID-19-Related Anosmia: A Pilot Study
F Sherif1, A H Elmokadem2, A Abdel Razek1
1From the Departments of Radiology (F.S., A.H.E., A.A.R., M.M.G.).
Abstract:
This study aimed to assess the utility of DTI in the detection of olfactory bulb dysfunction in COVID-19-related anosmia. It was performed in 62 patients with COVID-19-related anosmia and 23 controls. The mean diffusivity and fractional anisotropy were calculated by 2 readers. The difference between the fractional anisotropy and mean diffusivity values of anosmic and control olfactory bulbs was statistically significant (P = .001). The threshold of fractional anisotropy and mean diffusivity to differentiate a diseased from normal olfactory bulb were 0.22 and 1.5, with sensitivities of 84.4% and 96.8%, respectively, and a specificity of 100%.
Related Concept Videos
Olfactory Receptors: Location and Structure
Physiology of Smell and Olfactory Pathway
The olfactory...
Olfaction
The olfactory receptors are embedded in the cilia of the...


