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Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

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Topical therapy for canine pyoderma: what is new?

Domenico Santoro¹

¹Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL.

Journal of the American Veterinary Medical Association

|March 15, 2023

Summary

Topical antimicrobials are crucial for treating canine pyoderma, reducing the need for systemic antibiotics. This review explores classic and new options to combat antimicrobial resistance in veterinary dermatology.

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Area of Science:

Veterinary Dermatology
Antimicrobial Resistance
Bacteriology

Background:

Increasing prevalence of antimicrobial-resistant cutaneous infections in veterinary medicine.
Need to limit systemic antibiotic use for canine pyoderma to reduce resistance.
Established topical antimicrobials (chlorhexidine, benzoyl peroxide, ethyl lactate) have limitations.

Approach:

Systematic review of current knowledge on topical treatments for canine pyoderma.
Evaluation of antibacterial efficacy and clinical use of "classic" and novel agents.
Focus on filling knowledge gaps since previous reviews a decade ago.

Key Points:

Exploration of both traditional and emerging topical antimicrobial therapies.
Emphasis on low-resistance profile agents to mitigate multidrug-resistant bacteria selection.
Clinical data on newer alternatives is still emerging.

Conclusions:

Significant need for effective topical alternatives to systemic antibiotics in canine pyoderma treatment.
Desire to reduce overall antibiotic usage in veterinary medicine for antimicrobial stewardship.
This review provides a contemporary overview to guide clinical practice and future research.