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Updated: Aug 6, 2025

Isolation of Leukocytes from the Human Maternal-fetal Interface
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IL-33 is alarmin the uterus for labor

Elizabeth A Kennedy1, Kellie Ann Jurado1

  • 1Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.

Immunity
|March 15, 2023
PubMed

Timely labor is critical for both infant and maternal health, yet the mechanisms underlying the initiation of childbirth remain unclear. In this issue of Immunity, Siewiera et al. demonstrate a vital role for innate type 2 immune responses in controlling uterus-intrinsic onset of labor in mice.1.

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