Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

4.7K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.7K
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

53
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
53
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

71
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
71
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

4.9K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility and Yield of a Diagnostic Protocol for Myocardial Infarction with Non-Obstructive Coronary Arteries.

The American journal of cardiology·2026
Same author

Cardiac Allograft Vasculopathy: 5-Year Longitudinal Morphological Changes Assessed by Optical Coherence Tomography.

JACC. Asia·2026
Same author

Glucagon-like peptide-1 receptor agonists reduce experimental atherosclerosis progression, inflammatory biomarkers and cardiovascular events, irrespective of hyperglycaemia and obesity.

European heart journal·2026
Same author

Short-term lesion-level impact of extensive LDL-C reduction with statins and PCSK9 inhibitors: a pre-specified subgroup analysis of the randomized FITTER trial.

Clinical research in cardiology : official journal of the German Cardiac Society·2026
Same author

Label-free subcellular imaging with dynamic spectrally encoded confocal microscopy (D-SECM) with subpixel jitter correction.

Biomedical optics express·2026
Same author

Age- and Sex-Specific Distribution and Reference Values of Coronary Artery Calcium in a Large Asymptomatic Japanese Cohort.

Journal of the American Heart Association·2026
Same journal

Optimizing Utilization and Minimizing Risk: The Next Era of Mechanical Circulatory Support Devices.

Interventional cardiology clinics·2026
Same journal

Foreword.

Interventional cardiology clinics·2026
Same journal

Future Directions in Temporary Mechanical Circulatory Support for Cardiogenic Shock: Novel Devices and Evolving Therapeutic Paradigms.

Interventional cardiology clinics·2026
Same journal

Prevention and Management of Acute Limb Ischemia when Using Temporary Mechanical Circulatory Support Devices.

Interventional cardiology clinics·2026
Same journal

Prevention and Management of Hemolysis when Utilizing Mechanical Circulatory Support.

Interventional cardiology clinics·2026
Same journal

Optimal Large-Bore Vascular Access and Closure for Percutaneous Mechanical Circulatory Support in Cardiogenic Shock.

Interventional cardiology clinics·2026
See all related articles

Related Experiment Video

Updated: Aug 6, 2025

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

7.7K

OCT Emerging Technologies: Coronary Micro-optical Coherence Tomography.

Kensuke Nishimiya1, Radhika K Poduval2, Guillermo J Tearney3

  • 1Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, Japan.

Interventional Cardiology Clinics
|March 15, 2023
PubMed
Summary
This summary is machine-generated.

Micro-Optical Coherence Tomography (μOCT) offers higher resolution imaging for interventional cardiology. This advanced technique visualizes coronary microstructures previously unseen by standard OCT, aiding in procedure understanding.

Keywords:
Cholesterol crystalsEndothelial cellsInflammatory cellsMacrophageMicro-OCT (μOCT)Optical coherence tomography (OCT)Plaque erosion

More Related Videos

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
14:21

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation

Published on: January 22, 2013

14.2K
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.2K

Related Experiment Videos

Last Updated: Aug 6, 2025

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

7.7K
Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation
14:21

Optical Frequency Domain Imaging of Ex vivo Pulmonary Resection Specimens: Obtaining One to One Image to Histopathology Correlation

Published on: January 22, 2013

14.2K
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

4.2K

Area of Science:

  • Cardiovascular Imaging
  • Biomedical Optics
  • Interventional Cardiology

Background:

  • Optical Coherence Tomography (OCT) is crucial in interventional cardiology.
  • Clinical OCT resolution limits visualization of key coronary vessel wall components.
  • Cellular-level changes within the vessel wall are currently undetectable.

Purpose of the Study:

  • To review the capabilities of micro-OCT (μOCT) for visualizing coronary microstructures.
  • To discuss the clinical implications of μOCT in interventional cardiology.
  • To highlight μOCT's potential to overcome resolution limitations of conventional OCT.

Main Methods:

  • Review of existing literature on micro-OCT technology.
  • Analysis of μOCT's resolution capabilities (1-2 μm).
  • Comparison of μOCT imaging with standard OCT in coronary applications.

Main Results:

  • μOCT achieves significantly higher resolution than clinical OCT.
  • μOCT can visualize cellular and subcellular structures within the vessel wall.
  • Demonstration of μOCT's ability to detect specific cell types like neutrophils and macrophages.

Conclusions:

  • μOCT technology provides unprecedented visualization of coronary microstructures.
  • This enhanced resolution has significant potential clinical implications for interventional cardiology.
  • μOCT may improve diagnosis and treatment guidance in complex cardiovascular procedures.