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Updated: Aug 6, 2025

Author Spotlight: Isolating Biomolecules from Mouse Tears — A Methodology for Molecular Analysis and Biomarker Research
Published on: July 19, 2024
[Features of water-electrolyte component of the tear fluid]
1Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Abstract:
Tear production is a complex multi-step process that can be arbitrarily divided into three stages: «primary» secretion by the acinar cells of the main lacrimal glands, formation of «secondary» lacrimal fluid in the ducts of the main lacrimal glands, and «tertiary» modification of the tear composition in the conjunctival sac. This article highlights mechanisms of water and electrolytes secretion in the process of tear fluid production and describes the particularities of distribution of the membrane transport proteins in the lacrimal gland and the ocular surface.
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