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Antioxidant polysaccharide/gelatin blend films loaded with curcumin - A comparative study
Katarzyna Łupina1, Dariusz Kowalczyk1, Magdalena Lis2
1Department of Biochemistry and Food Chemistry, Faculty of Food Sciences and Biotechnology, University of Life Sciences in Lublin, Skromna 8, 20-704 Lublin, Poland.
International Journal of Biological Macromolecules
|March 16, 2023
Summary
This study developed polysaccharide-gelatin blend films for curcumin delivery. The CMC75/GEL25 film showed fast curcumin release and good mechanical properties, while GAR films offered superior transparency.
Area of Science:
- Food Science and Technology
- Materials Science
- Biopolymer Engineering
Background:
- Polysaccharide-gelatin blends are promising for active packaging.
- Curcumin (CUR) is a bioactive compound with antioxidant and UV-protective properties.
- Controlling CUR release and film properties is crucial for effective application.
Purpose of the Study:
- To develop and characterize binary blend films of various polysaccharides and gelatin for curcumin encapsulation.
- To evaluate the effect of CUR on film properties, including mechanical strength, transparency, and UV-barrier characteristics.
- To investigate CUR release kinetics and the antiradical activity of the developed films.
Main Methods:
- Preparation of blend films using carboxymethyl cellulose (CMC), gum Arabic (GAR), octenyl succinic anhydride modified starch (OSA), water-soluble soy polysaccharides (WSSP), and gelatin (GEL) at a 75:25 ratio.
- Incorporation of varying concentrations of curcumin (0-0.02%).
- Characterization using surface roughness analysis, UV-Vis spectroscopy, X-ray diffractometry, mechanical testing, and antiradical activity assays (DPPH*).
Main Results:
- Gum Arabic (GAR)-based films exhibited the lowest roughness and highest transparency, while WSSP-based films showed the opposite.
- Carboxymethyl cellulose (CMC75)/GEL25 films demonstrated excellent mechanical strength despite phase separation.
- Curcumin improved UV/VIS light barrier properties and induced structural rearrangement in gelatin.
- CMC75/GEL25 films provided the fastest CUR release due to high erodibility, whereas OSA75/GEL25 showed slower release.
- All CUR-supplemented films displayed comparable antiradical potential, with CMC75/GEL25 showing the highest colorimetric stability.
Conclusions:
- Polysaccharide-gelatin blends offer tunable properties for curcumin delivery systems.
- The CMC75/GEL25 system is a promising carrier for rapid curcumin release and enhanced UV protection.
- Film composition significantly influences physical properties, CUR release, and stability, impacting potential applications in food or biomedical fields.
