Update on Lentigo Maligna: Diagnostic Signs and Treatment.

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Lentigo maligna is an early-stage melanoma developing on sun-exposed skin, often affecting older individuals.
• It typically appears as a slow-growing, irregularly pigmented lesion, primarily on the face.
• Progression to invasive melanoma is estimated to occur in 2-5% of cases.

Purpose of the Study:

• To review clinical and histopathological findings aiding Lentigo maligna diagnosis.
• To examine current treatment strategies for Lentigo maligna, emphasizing surgical approaches.

Main Methods:

• Review of clinical presentations of Lentigo maligna.
• Analysis of histopathological diagnostic criteria.
• Evaluation of surgical treatment options and their outcomes.

Main Results:

• Diagnosis can be challenging due to early-stage or atypical presentations.
• Lesion location in visible areas and large size complicate treatment.
• Surgery may impact cosmetic and functional results in highly visible areas.

Conclusions:

• Accurate diagnosis relies on careful evaluation of clinical and histopathological features.
• Treatment decisions for Lentigo maligna require balancing efficacy with cosmetic and functional considerations.
• Further research may refine diagnostic and therapeutic strategies for this melanoma subtype.