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Circulating immune complexes in cancer patients
S Jaramillo1, M Shafir, G Bekesi
1Department of Surgery, Mount Sinai School of Medicine, New York, N.Y.
Immunological Investigations
|August 1, 1987
Abstract:
Circulating Immune Complexes (CIC) have been described in malignant diseases. To elucidate their potential clinical significance, CIC of seventy-eight patients with cancer and of seventy-one normal individuals were studied. Total protein and immunoglobulin composition of CIC were quantitatively measured. Patients sera had consistently higher titers of CIC than normal individuals. Sodium Dodecyl Sulfate/Polyacrylamide Gel Electrophoresis (SDS/PAGE) showed subtle differences in the CIC protein composition between patients and normal individuals.