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Cancer Proteomics for Cellular Dysfunction: Insights and Trends.

Anjna Rani1, Veena Devi Singh2, Rupa Mazumder1

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Summary

Proteomics, a key technique in cancer biology, aids in identifying biomarkers for early cancer detection. Advances in mass spectrometry enable precise protein analysis, paving the way for improved cancer diagnostics.

Keywords:
Proteomicsapplicationsbiomarkersmolecular pathwayspatents related to cancer proteomicsthe technology of proteomics

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Area of Science:

  • Cancer Biology
  • Proteomics
  • Biomarker Discovery

Background:

  • Cancer's low survival rate is linked to late-stage diagnosis.
  • Early detection through routine biomarker identification is crucial for improving prognosis.
  • Proteomic analysis is emerging as a vital tool in cancer research, complementing genomic studies.

Approach:

  • An extensive literature review was performed using Google Scholar, Science Direct, and PubMed.
  • Keywords included proteomics, its applications, technology, biomarkers, and related patents.
  • Studies published up to 2021 focusing on cancer proteomics and patents were analyzed.

Key Points:

  • Mass spectrometry allows for precise quantitative and qualitative identification of numerous proteins in biological samples.
  • Proteomics offers new avenues for biomarker investigation.
  • Technological advancements in proteomics are driving progress in cancer research.

Conclusions:

  • Proteomics is instrumental in identifying cancer biomarkers and characterizing molecular pathways.
  • While promising, the application of proteomics in routine cancer diagnostics is still in its early stages.
  • This review provides insights into cancer proteomics and its potential for future diagnostic techniques.