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Updated: Aug 6, 2025
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Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection
Published on: November 22, 2013
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Legionnaires' disease in the EU/EEA*: increasing trend from 2017 to 2019
Jonas Samuelsson1, Lara Payne Hallström1, Gaetano Marrone1
1European Centre for Disease Prevention and Control, Stockholm, Sweden.
Summary
Legionnaires
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- European Surveillance
Background:
- Legionnaires' disease (LD) burden has risen in the EU/EEA over the past decade.
- Notification rates increased from 1.2-1.4/100,000 (2012-16) to 1.8-2.2/100,000 (2017-19).
Purpose of the Study:
- To quantify excess weekly Legionnaires' disease cases in 2017-19.
- To identify significant trend changes in LD incidence.
- To analyze demographic and import status differences in LD cases.
Main Methods:
- Utilized European Surveillance System (TESSy) data (2012-19).
- Employed dynamic regression for retrospective prediction (2012-16 data).
- Applied Interrupted Time Series (ITS) analysis to detect trend shifts.
Main Results:
- Observed a 33.9% increase in cases during 2017-19 versus predictions.
- ITS analysis confirmed a significant increasing trend in 2017-19 compared to 2012-16.
- Trend increase was most pronounced in individuals over 60 and non-imported cases.
Conclusions:
- A significant upward trend in Legionnaires' disease cases occurred in the EU/EEA (2017-19).
- Seasonal trends appear amplified, suggesting increased transmission.
- Legionnaires' disease remains a public health concern requiring further investigation.
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